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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
2000 1
2002 1
2014 2
2015 2
2017 2
2018 3
2019 2
2020 5
2021 1
2022 2
2024 2

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18 results

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Page 1
TYRO protein tyrosine kinase-binding protein predicts favorable overall survival in osteosarcoma and correlates with antitumor immunity.
Xu HR, Chen JJ, Shen JM, Ding WH, Chen J. Xu HR, et al. Medicine (Baltimore). 2022 Sep 30;101(39):e30878. doi: 10.1097/MD.0000000000030878. Medicine (Baltimore). 2022. PMID: 36181123 Free PMC article.
To explore the prognostic significance and underlying mechanism of TYRO protein tyrosine kinase-binding protein (TYROBP) in osteosarcoma. ...TYROBP was significantly increased in osteosarcoma (all P < .001). ...
To explore the prognostic significance and underlying mechanism of TYRO protein tyrosine kinase-binding …
Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice.
Zhang SS, Zhu L, Peng Y, Zhang L, Chao FL, Jiang L, Xiao Q, Liang X, Tang J, Yang H, He Q, Guo YJ, Zhou CN, Tang Y. Zhang SS, et al. J Neuroinflammation. 2022 Feb 5;19(1):34. doi: 10.1186/s12974-022-02401-5. J Neuroinflammation. 2022. PMID: 35123512 Free PMC article.
The expression levels of microglial glucose transporter (GLUT5), TREM2, soluble TREM2 (sTREM2), TYRO protein tyrosine kinase binding protein (TYROBP), secreted phosphoprotein 1 (SPP1), and phosphorylated spleen tyrosine k …
The expression levels of microglial glucose transporter (GLUT5), TREM2, soluble TREM2 (sTREM2), TYRO protein tyrosine …
TYROBP in Alzheimer's disease.
Ma J, Jiang T, Tan L, Yu JT. Ma J, et al. Mol Neurobiol. 2015 Apr;51(2):820-6. doi: 10.1007/s12035-014-8811-9. Epub 2014 Jul 23. Mol Neurobiol. 2015. PMID: 25052481 Review.
Recently, studies have provided convincing data that TYRO protein tyrosine kinase-binding protein (TYROBP), a key regulator in immune systems, is significantly upregulated in the brain of patients with Alzheimer's disease (AD). …
Recently, studies have provided convincing data that TYRO protein tyrosine kinase-binding protein …
Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy.
Paloneva J, Autti T, Hakola P, Haltia MJ. Paloneva J, et al. 2002 Jan 24 [updated 2020 Dec 10]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2002 Jan 24 [updated 2020 Dec 10]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301376 Free Books & Documents. Review.
If both parents are known to be heterozygous for a TREM2 or TYROBP pathogenic variant, each sib of an affected individual has at conception a 25% chance of being affected, a 50% chance of being an asymptomatic carrier, and a 25% chance of being unaffected and not a …
If both parents are known to be heterozygous for a TREM2 or TYROBP pathogenic variant, each sib of an affected individual has at conc …
IGFBP6 Is Downregulated in Unstable Carotid Atherosclerotic Plaques According to an Integrated Bioinformatics Analysis and Experimental Verification.
Liu Y, Huan W, Wu J, Zou S, Qu L. Liu Y, et al. J Atheroscler Thromb. 2020 Oct 1;27(10):1068-1085. doi: 10.5551/jat.52993. Epub 2020 Feb 8. J Atheroscler Thromb. 2020. PMID: 32037372 Free PMC article.
Collagen type I alpha 2 chain (COL1A2), adenylate cyclase 3 (ADCY3), C-X-C motif chemokine receptor 4 (CXCR4), and TYRO protein tyrosine kinase binding protein (TYROBP) might play crucial roles in the PPI networks. In drug-gene int …
Collagen type I alpha 2 chain (COL1A2), adenylate cyclase 3 (ADCY3), C-X-C motif chemokine receptor 4 (CXCR4), and TYRO protein …
Alzheimer's disease pathology in Nasu-Hakola disease brains.
Satoh JI, Kino Y, Yanaizu M, Saito Y. Satoh JI, et al. Intractable Rare Dis Res. 2018 Feb;7(1):32-36. doi: 10.5582/irdr.2017.01088. Intractable Rare Dis Res. 2018. PMID: 29552443 Free PMC article.
Nasu-Hakola disease (NHD) is a rare autosomal recessive disorder, characterized by progressive presenile dementia and formation of multifocal bone cysts, caused by genetic mutations of either triggering receptor expressed on myeloid cells 2 (TREM2) or TYRO protein …
Nasu-Hakola disease (NHD) is a rare autosomal recessive disorder, characterized by progressive presenile dementia and formation of multifoca …
Deciphering the molecular and clinical characteristics of TREM2, HCST, and TYROBP in cancer immunity: A comprehensive pan-cancer study.
Zheng P, Tan Y, Liu Q, Wu C, Kang J, Liang S, Zhu L, Yan K, Zeng L, Chen B. Zheng P, et al. Heliyon. 2024 Feb 28;10(5):e26993. doi: 10.1016/j.heliyon.2024.e26993. eCollection 2024 Mar 15. Heliyon. 2024. PMID: 38468942 Free PMC article.
BACKGROUND: Hematopoietic cell signal transducer (HCST) and tyrosine kinase-binding protein (TYROBP) are triggering receptors expressed on myeloid cells 2 (TREM2), which are pivotal in the immune response to disease. Despite growing evidence und …
BACKGROUND: Hematopoietic cell signal transducer (HCST) and tyrosine kinase-binding protein (TYROBP) are …
Deciphering microglial activation and neuronal apoptosis post-traumatic brain injury: The role of TYROBP in inflammation regulation networks.
Zhou X, Song H, He J, Han W, Li Q. Zhou X, et al. Mol Med Rep. 2024 Jun;29(6):104. doi: 10.3892/mmr.2024.13228. Epub 2024 Apr 19. Mol Med Rep. 2024. PMID: 38639190
The present study analyzed rat and mouse RNA expression micro-arrays, high-throughput RNA sequencing and single-cell sequencing data sourced from public databases. To construct an inflammation regulation network around TYRO protein tyrosine kinase-b …
The present study analyzed rat and mouse RNA expression micro-arrays, high-throughput RNA sequencing and single-cell sequencing data sourced …
Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.
Paloneva J, Kestilä M, Wu J, Salminen A, Böhling T, Ruotsalainen V, Hakola P, Bakker AB, Phillips JH, Pekkarinen P, Lanier LL, Timonen T, Peltonen L. Paloneva J, et al. Nat Genet. 2000 Jul;25(3):357-61. doi: 10.1038/77153. Nat Genet. 2000. PMID: 10888890
Here we characterize the molecular defect in PLOSL by identifying one large deletion in all Finnish PLOSL alleles and another mutation in a Japanese patient, both representing loss-of-function mutations, in the gene encoding TYRO protein tyrosine kinase …
Here we characterize the molecular defect in PLOSL by identifying one large deletion in all Finnish PLOSL alleles and another mutation in a …
18 results